MOTS-C

MOTS-c (Research Grade)

Product Overview:

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a naturally occurring mitochondrial-derived peptide composed of 16 amino acids. Unlike most peptides encoded by the nuclear genome, MOTS-c is unique in its origin from the mitochondrial DNA. In molecular research, it is utilized as a vital tool to study the "retrograde signaling" between mitochondria and the cell nucleus.

Key Technical Specifications:

• Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Ala-Leu-Lys-Ile-Cys-Glu

• Molecular Formula: C101 H152 N28 O22 S2

• Purity: ≥99% (HPLC Verified)

• Format: Lyophilized Powder

• Storage: Store at -20°C for long-term stability; protect from moisture.

Primary Research Applications:

This compound is intended strictly for in vitro and animal research models to investigate:

• Mitochondrial Signaling: Studying how mitochondrial-derived peptides regulate nuclear gene expression and cellular homeostasis.

• Metabolic Flux: Investigating the peptide's influence on the AMPK (Adenosine Monophosphate-activated Protein Kinase) signaling pathway.

• Glucose Homeostasis: Observing the modulation of glucose uptake and insulin-signaling kinetics in isolated cell cultures.

• Proteomic Integrity: Researching the role of MOTS-c in maintaining proteostasis during cellular stress.

Handling & Storage:

• Store in a controlled, low-temperature environment

• Avoid repeated exposure to heat, moisture, and light

• Handle using appropriate laboratory procedures

Compliance & Safety Disclaimer:

This product is supplied in accordance with industry-standard research material practices.

By purchasing, the customer confirms that:

• They are acquiring this material for legitimate laboratory use only

• They understand the product is not approved for human or veterinary use

• They will handle and use the material in compliance with applicable regulations

For laboratory research use only. Not for human or veterinary use.